Long-Term Effects of Chronic Oral Ritalin Administration on Cognitive and Neural Development in Adolescent Wistar Kyoto Rats

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Long-Term Effects of Chronic Oral Ritalin Administration on Cognitive and Neural Development in Adolescent Wistar Kyoto Rats

The diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) often results in chronic treatment with psychostimulants such as methylphenidate (MPH, Ritalin®). With increases in misdiagnosis of ADHD, children may be inappropriately exposed to chronic psychostimulant treatment during development. The aim of this study was to assess the effect of chronic Ritalin treatment on cognitive and neur...

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The effect of oral administration of morphine on the development of neural plate in Wistar rats

Morphine administration produces several behavioral abnormalities in children and also in offspring animals, which is referred to as the effects of the drug on the development of the central nervous system. In the present study, the effect of maternal morphine consumption on the development of neural plate was investigated in Wistar rats (200-250 g). For this purpose, female rats (n = 8) were t...

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The effect of oral administration of morphine on the development of neural plate in Wistar rats

Morphine administration produces several behavioral abnormalities in children and also in offspring animals, which is referred to as the effects of the drug on the development of the central nervous system. In the present study, the effect of maternal morphine consumption on the development of neural plate was investigated in Wistar rats (200-250 g). For this purpose, female rats (n = 8) were t...

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The effect of oral morphine administration on development of neural tube in Wistar rats

Morphine administration during pregnancy causes several behavioral abnormalities in offspring animals. In the present study the effects of maternal morphine consumption on development of neural tube in Wistar rats (250-300 g) were investigated. Female rats (n = 8 were crossed with male rats and pregnant ones were treated with oral morphine (0.01, 0.05 and 0.1 mg/ml of water) until the 10th day ...

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ژورنال

عنوان ژورنال: Brain Sciences

سال: 2012

ISSN: 2076-3425

DOI: 10.3390/brainsci2030375